Studies which are Now Recruiting

The Geriatric Health Services Research Lab is conducting a research study to explore how the Riding in the Moment horseback riding program can be adapted to include adults with Down syndrome.

The purpose of the research study is to create a fun, easy-to-use mobile app to support healthy habits in teens and young adults with Down syndrome.

This study is testing whether a medicine called abrocitinib can help people 12 years and older with Down syndrome treat alopecia areata (hairloss) and symptoms of atopic dermatitis (eczema).

The team is interested in studying the early development of language and motor skills in children with and without Down Syndrome.

The goal of this study is to understand the development of challenging behaviors in children with Down syndrome. Caregivers will complete questionnaires about their child. Children will take part in an in-person EEG and problem-solving task visit.

This research study is investigating how six months of oxygen treatment while sleeping affects individuals 5 to 17 years old with Down syndrome. The study will look at sleep, breathing, heart function, quality of life, and whether the treatment if it makes them feel better. The team also wants to see if the oxygen helps decrease the severity of participants' obstructive sleep apnea (OSA).

Down Syndrome Regression Disorder (DSRD) is a rare condition that can affect adolescents and adults with Down syndrome, resulting in the loss of language, adaptive skills, and social behaviors. This study will look at the safety and effectiveness of three different possible therapies for DSRD: lorazepam, IVIG, and tofacitinib.

This observational study will help researchers better understand the everyday movements and activities of infants with Down syndrome and track their motor skills over time.

This study investigates brain changes related to development in children and adults with Down syndrome.

The Alzheimer’s Clinical Trials Consortium-Down Syndrome (ACTC-DS) invites you to participate in the Trial-Ready Cohort-Down Syndrome (TRC-DS). TRC-DS is a community of potential clinical trial volunteers who could help find a cure for Alzheimer’s disease.

The goal of this study is to learn how the ability to walk with mobility devices develops in infants and toddlers with Down syndrome, which will guide the design of early interventions to support walking development.

The goal of this study is to learn about differences in thinking, learning, and behavior for individuals with Down syndrome with and without a history of childhood cancer; we are recruiting parents of individuals with Down syndrome and no history of childhood cancer for this part of the study.

This study aims to teach us how to improve services for individuals with Down syndrome who find it hard to be understood through speech and/or experience regular problems with choking on food or liquid. We also seek to understand how the brain helps to control swallowing and speech production.

This is a VIRTUAL three-month intervention study of the effects of a smartphone application (HippoCamera) on personal event memory in teens and young adults with Down syndrome.

The study’s goal is to improve the way we engage individuals with Down syndrome in conversations about healthcare and empower them in medical decision-making.

Caregivers of children with Down syndrome 2 to 17 years old are invited to complete a survey helping develop the first-ever tool measuring challenging behavior that is specifically made FOR children with Down syndrome and created WITH the Down syndrome community.

Researchers at Drexel University are conducting a study to learn more about how cognitive and behavioral factors influence employment outcomes and independent living skills in young adults with Down syndrome.