The purpose of this study is to test how well personalized surgical treatment helps children with Down syndrome (DS) who have obstructive sleep apnea (OSA).
Who can participate in this study?
Children with Down syndrome may participate if they:
- Are between 2 and 17 years old
- Have been diagnosed with obstructive sleep apnea (OSA
Who cannot participate in this study?
- Anyone who has had a previous partial or total tonsillectomy
Contact the study team for additional eligibility criteria.
Where does this study take place?
- Oregon Health & Science University, Portland, OR
- University of Michigan, Ann Arbor, Ml
- University of Texas - Southwestern Medical Campus, Dallas, TX
- Eastern Virginia Medical School, Norfolk, VA
- Children's Hospital Colorado, Aurora, CO
- Texas Children's Hospital, Houston, TX
What activities are involved in this study?
Participants in this study will:
- Complete a sleep study to determine eligibility and another sleep study 6 months after surgery
- Either standard removal of tonsils and adenoids or a personalized surgical treatment
- Attend clinic visits before and after surgery, which include completing questionnaires and online checkins
What languages does this study support?
English and Spanish
Is compensation provided?
Yes
To learn more, visit our TOPS Study Page. If you have any questions or are interested in joining the study, please contact the research team at oneilele@ohsu.edu.
Principal investigator
Derek Lam, MD, MPH
Publish Date