Adult (18+)

Modulation of the Immune System in Down Syndrome for Improved Outcomes and Neurodevelopment-1 Study (MISSION-1) will evaluate a six-month treatment of a medicine called tofacitinib to see if it can improve the health of individuals with Down syndrome.

This study explores how children with Down syndrome in remission from leukemia and their families experience survivorship, focusing on their daily lives, support systems and strengths and skills gained through their experience.

The Down Syndrome Health Measure (DSHM) is a new, short survey that was created specifically with people with Down syndrome in mind, and asks questions about aspects of overall health. Now that this final measure is available, we’re interested in collecting feedback on the survey from caregivers of individuals with Down syndrome age 0 to 21.

Family caregivers of adults living with Down syndrome or another intellectual disability who are experiencing memory changes are invited to participate in CarePRO Virtual-DS/ID, a free 5-week online workshop designed to reduce distress and improve quality of life.

The purpose of this study is to focus on how individuals from the Down syndrome community (caregivers and self-advocates) understand how to participate in research studies, how they perceive research studies, and how past experiences shape their decisions in participating in research studies.

The study is evaluating hearing, speech, and language for people with Down syndrome of all ages.

This research study aims to understand whether families of individuals with Down syndrome have received education from healthcare providers about the risk of infantile spasms and to identify if there are geographic or demographic differences in who receives this information.

The purpose of this study is to understand how doctors, patients with Down syndrome, and their supporters talk to each other during clinic visits.

Adults with Down syndrome will play games and do simple activities on the computer, on paper, and with board games. These activities help researchers learn how people think and solve problems. Parents or caregivers will answer questions about everyday skills, like memory and daily routines.

The Brain Outcomes and Lifestyle in Down syndrome (BOLD) study aims to understand how dietary changes and weight impact the risk of Alzheimer's disease in adults with Down syndrome.